Description
High-purity Harmine, a β-carboline alkaloid naturally found in Peganum harmala, showing significant antitumor potential and various pharmacological properties.
Technical Specifications
- Molecular Formula: C₁₃H₁₂N₂O
- Molecular Weight: 212.25 g/mol
- Purity: ≥98% (HPLC)
- Appearance: White to off-white crystalline powder
- Solubility: Soluble in DMSO, and methanol; poorly soluble in water
IUPAC Name: 7-methoxy-1-methyl-9H-pyrido[3,4-b]indole
InChI: InChI=1S/C13H12N2O/c1-8-13-11(5-6-14-8)10-4-3-9(16-2)7-12(10)15-13/h3-7,15H,1-2H3
InChIKey: BXNJHAXVSOCGBA-UHFFFAOYSA-N
Canonical SMILES: CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
Isomeric SMILES: CC1=NC=CC2=C1NC3=C2C=CC(=C3)OC
Synonyms: HARMINE; 442-51-3; 7-Methoxy-1-methyl-9H-pyrido[3,4-b]indole; Banisterine; Telepathine; Leucoharmine; Yageine; Yajeine; …
Botanical Source: Peganum harmala L.Seeds
Key Features & Benefits
- Natural β-carboline alkaloid
- Multiple pharmacological effects
- Strong antitumor properties
- DNA topoisomerase I inhibitor
- Comprehensive Certificate of Analysis
Research Applications
-
Cancer Research
- Cell proliferation studies
- Survival mechanism research
- Angiogenesis investigations
- Migration/invasion studies
-
Pharmaceutical Development
- Drug resistance studies
- Novel formulation research
- Mechanism investigations
- Combination therapy studies
-
Neuroscience Research
- Neurotoxicity studies
- Brain protection research
- Neural pathway investigations
- Cognitive function studies
Storage & Handling
- Store at -20°C
- Protect from light
- Avoid repeated freeze-thaw cycles
- Stock solution guidelines provided
- 24-month stability under recommended conditions
Key Research Areas
-
Disease Applications
- Cancer therapy
- Neurodegenerative conditions
- Drug resistance
- Cell signaling pathways
-
Molecular Mechanisms
- Anti-proliferative effects
- Apoptosis pathways
- Angiogenesis inhibition
- Cell migration control
Quality Assurance
- GMP-compliant manufacturing
- Rigorous quality control
- Complete analytical documentation
- Traceable lot numbers
- Stability monitoring program
Package Sizes
- 5mg
- 10mg
- 25mg
- 100mg
- Bulk quantities available
Research Support
BIORLAB provides:
- Technical consultation
- Analytical method support
- Stability data
- Custom synthesis options
- Application Guidance
This premium-grade Harmine is designed for research institutions and pharmaceutical companies advancing therapeutic development.
For research and development purposes only. Not for human consumption or clinical use.